Mesotherapy is a technique designed to dissolve fat within the body with the use of injected amino acids and medications. The name comes from the fact that the injections are made into the mesoderm, the middle layer of skin. This technique can be used to treat many conditions, depending on what is injected into the body and where. For fat reduction, a specific combination of amino acids and medicines are injected directly into the skin to target the unwanted fat.

Mesotherapy is sometimes used to treat cellulite and fat deposits in the legs, hips, thighs, arms, abdomen, and the face. The injected medicine breaks down the connective bonds of adipose fat cells so they can naturally be flushed out of the body. Over time, patients see a reduction in fat in the treated areas.

Because the injection targets the fat directly, only a small amount of medicine is injected. The concentration of the injected fluid and the number of treatments needed depend on the area being treated and the desired outcome.

Mesotherapy is minimally invasive and, for most patients, nearly painless because very small needles are used for the injections. Since the injected medicine works underneath the epidermis, or outer layer of skin, there are no scars though some patients may experience irritation and bruising at the injection site. Depending on the desired outcome, multiple treatments may be needed over the course of several weeks or months. Individual treatments typically take less than an hour and the patient can return to normal activities.

The results are not permanent. The fat can come back, especially if the patient does not follow a healthy diet and participate in regular exercise. A healthy lifestyle will help maintain the results but additional treatments will likely be needed.

Mesotherapy is popular in Europe and South America. It was pioneered in the 1952 by Dr. Michel Pistor in France. It has been practiced in the United States for the last several years.